RecruitingNCT06698146

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study


Sponsor

Northwestern University

Enrollment

80 participants

Start Date

Aug 27, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal of this study is to look at and compare the clinical results of all the different approved methods (living vs. Deceased, whole organ vs. Split, one staged vs. Two staged) used to perform a standard liver transplant procedure for recipients with CRLM. Investigators will look at things like different procedure results, recovery in the hospital, and survival rates one year after the transplant. Investigators will also take blood samples from participants to be used in future research. All the transplant methods the investigators are comparing are standard practices approved by the United Network of Organ Sharing (UNOS).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a complex surgical approach for people with colorectal cancer that has spread to the liver, involving a liver transplant combined with a delayed removal of the original colon tumor, for patients who have not responded to other treatments. **You may be eligible if...** - You are 18 years or older - You have been placed on the liver transplant waitlist at Northwestern due to colorectal cancer that has spread to the liver - You are able to provide your own informed consent **You may NOT be eligible if...** - You are unable to give consent yourself - You are pregnant - Certain clinical, surgical, or anatomical factors make you unsuitable, as determined by the study doctor Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Northwestern University-Comprehensive Transplant Center

Chicago, Illinois, United States

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NCT06698146


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