RecruitingNot ApplicableNCT06699030

A Strategy for Gallstone Expulsion Through Dietary Therapy

A New Strategy for Gallstone Expulsion Through Dietary Therapy: A Prospective, Single-Center, Double-Blind, Randomized Controlled Trial


Sponsor

Hepatopancreatobiliary Surgery Institute of Gansu Province

Enrollment

100 participants

Start Date

Dec 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria1

  • Gallbladder sludge-like stones with a maximum stone diameter of less than 2 mm

Exclusion Criteria22

  • History of ERCP (Endoscopic Retrograde Cholangiopancreatography)
  • Previous gallstone removal surgery with gallbladder preservation
  • History of acute or chronic pancreatitis, cholangitis
  • Mirizzi Syndrome
  • History of gastrointestinal surgery
  • Gastrointestinal obstruction
  • Dysfunction of the sphincter of Oddi
  • Gallbladder neck polyps
  • Abnormal gallbladder structure
  • Gallbladder mass
  • Biliary infection or stones
  • Congenital biliary abnormalities
  • Biliary injury or surgery
  • Biliary tumors
  • Gastrointestinal bleeding, liver cirrhosis, or other malignant diseases
  • Significant arrhythmia, bradycardia, or atrioventricular block
  • Severe hypertension, liver or kidney insufficiency
  • Immune, endocrine, hematological, or mental disorders
  • Severe cerebrovascular disease
  • Allergy to relevant foods
  • Pregnant or breastfeeding women
  • Unwillingness or inability to consent to participation

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Interventions

DRUGFunctional fatty acids

Days 1-3: Oral Administration of functional fatty acids Days 4-6: Oral Administration of functional fatty acids

OTHERPlacebo

Days 1-3: Placebo Days 4-6: Oral Administration of functional fatty acids


Locations(1)

Long Deng

Lanzhou, Gansu, China

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NCT06699030


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