RecruitingPhase 1NCT06700772

Histomorphometric and Radiographic Evaluation of Bone Following Maxillary Sinus Augmentation

Histomorphometric and Radiographic Assessment of Bone Following Maxillary Sinus Augmentation Using Bone Marrow Concentrate Cells From the Maxillary Tuberosity Mixed With Bovine Bone Versus Autogenous Bone Mixed With Bovine Bone: RCT


Sponsor

Cairo University

Enrollment

26 participants

Start Date

Dec 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Two groups of patients with posterior vertical deficient maxillary alveolar ridge with pneumatized sinus and needing dental implant . First group will be subjected to open sinus lifting using autogenous bone mixed with bone marrow aspirate concentrate cells from maxillary tuberosity and the second group will be subjected to open sinus lifting using autogenous bone mixed with bovine bone


Eligibility

Min Age: 20 YearsMax Age: 50 Years

Inclusion Criteria5

  • Patients with missing maxillary teeth with pneumatized sinus and remaining bone height <5mm
  • Patients with healthy systemic condition (Medically free)
  • Adequate inter-arch space for placement of the implant prosthetic part.
  • Good oral hygiene
  • Cooperative patients who are willing to commit for 6 months follow up

Exclusion Criteria6

  • Smokers
  • Pregnant females
  • Patient with medical condition that contraindicates surgical procedures.
  • Patients on medication that may interfere with healing (corticosteroids, bisphosphonate, Chemo/radio therapy).
  • Patients with habits that may jeopardize the implant longevity and affect the results of the study such as alcoholism or parafunctional habits.
  • Patients have chronic sinus disease.

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Interventions

PROCEDUREmixing bone marrow aspirate concentrate from maxillary tuberosity with bovine bone

open sinus lifting using bone marrow aspirate concentrate from maxillary tuberosity and mixing it with bovine bone .

PROCEDUREmixing autogenous bone with bovine bone

open sinus lifting using autogenous bone from retromolar area mixed with bovine bone


Locations(2)

Faculty of oral and dental medicine - cairo university

Cairo, New Cairo, Egypt

Faculty of oral and dental medicine - cairo university

Cairo, Egypt

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NCT06700772