RecruitingNot ApplicableNCT06703060

A Multi-Level Trauma-Informed Approach to Increase HIV Pre-exposure Prophylaxis Initiation Among Black Women

Trauma-Informed HIV Prevention for Black Women in Baltimore


Sponsor

Johns Hopkins Bloomberg School of Public Health

Enrollment

300 participants

Start Date

Feb 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

U.S. epidemiological data indicates that Black women are a high-risk HIV disparity group, yet initiation of novel prevention strategies like pre-exposure prophylaxis (PrEP) among this group is stagnant. Socio-structural challenges like intimate partner violence and gendered racism can constrain PrEP access among Black women, but few implementation studies have mitigated these challenges to improve PrEP initiation. The proposed research aims to implement and assess the effectiveness, implementation, and sustainability of a multilevel intervention to increase PrEP initiation among Black women with and without intimate partner violence in Baltimore.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria6

  • self-identified Black cisgender woman;
  • self-reported HIV-negative status, and
  • ≥18 years.
  • reports unprotected vaginal or anal sex in the past 6 months with a male sexual partner,
  • have at least one substantial HIV risk factor in the past 6 months according to the 2021 Centers for Disease Control (CDC) PrEP Eligibility Guidelines (i.e., HIV-positive sexual partner, recent bacterial Sexually Transmitted Disease (STD), 2+ sex partners, history of inconsistent or no condom use, commercial sex work, and residing in high HIV prevalence area or network), and
  • never taken PrEP

Exclusion Criteria2

  • non-English speaking and
  • currently living with HIV

Interventions

BEHAVIORALPeer Navigation Group

Participants randomized to the intervention will receive behavioral lifestyle education on topics related to biomedical HIV prevention. This will include 4 group sessions and 4 one-on-one sessions with a peer navigator.


Locations(1)

Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland, United States

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NCT06703060


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