RecruitingNCT06703736

Functional and Morphological Characterization of Multiple Osteochondromas Disorder

Misure di funzionalità e deformità Dell'Apparato Muscolo-scheletrico Come "Biomarkers" Per il Trattamento di Malattie Ortopediche/Accessible Measurements of Mobility and Deformity as Biomarkers for Orthopaedic Treatments


Sponsor

Istituto Ortopedico Rizzoli

Enrollment

60 participants

Start Date

May 21, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and functional parameters. The morphological and functional data, supplemented with clinical and postural data, will allow the characterization of the disease with an holistic approach that can provide important information to properly assess timing for surgical treatments and to improve the quality of life of these patients. Another goal of the study is the assessment and the validation of novel instruments and tools to measure joint mobility and bone deformity. These instruments should be easy-to-use and designed to be operated locally by the patients themselves and/or in small clinics by operators with little training and no specific high-technical knowledge. The final goal of the study is the assessment of the quality of life and balance perception of patients, using questionnaires.


Eligibility

Min Age: 6 YearsMax Age: 40 Years

Inclusion Criteria14

  • clinical and/or molecular diagnosis of Multiple Osteochondromas;
  • male and female subjects;
  • age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment;
  • collection of appropriate informed consent;
  • ability to walk a linear path without aids;
  • presence of multiple osteochondromas localized at lower limbs;
  • ability to undergo all procedures required by the protocol.
  • absence of neuro-muskuloskeletal or other limb-limiting conditions in the lower limbs;
  • male and female subjects;
  • age minors: 6-17 years at enrollment and adult age: 18-40 years at enrollment;
  • collection of appropriate informed consent;
  • ability to undergo all procedures required by the protocol.
  • Any reason which, in the opinion of the investigator, would result in the inability of the participant to comply with the protocol.
  • BMI equal to or greater than 30.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(1)

IRCCS Istituto Ortopedico Rizzoli

Bologna, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06703736