The Study of Ginkgo Leaf Dropping Pills and Huperzine a Injection Combined with Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain Injury
Wanbangde Pharmaceutical Group Co., LTD
50 participants
Apr 1, 2024
INTERVENTIONAL
Conditions
Summary
This study will conduct a single-center clinical trial to explore the initial therapeutic effect of ginkgo biloba dropping pills, huperzine A injection and median nerve electrical stimulation in patients with cognitive impairment.
Eligibility
Inclusion Criteria3
- Be over 18 years old
- Residual cognitive impairment due to brain injury
- No previous history of brain-related diseases except this one
Exclusion Criteria2
- The patient had severe underlying disease and unstable vital signs
- The patient was complicated with consciousness disorder and could not cooperate with cognitive function assessment ③ Allergic to drugs or contraindications in drug use ④ There are contraindications of median nerve electrical stimulation
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Interventions
Median nerve electrical stimulation is an electrical stimulation therapy in which the electrode is placed at the median nerve point 2cm above the carpal wrinkles on the palmar surface of the wrist joint. Generally, the right median nerve is used for electrical stimulation. Electrical stimulation improves cognitive function by stimulating neurons in the brain and improving information transmission between neurons. When electrical current stimulates the brain, it can increase the activity level of neurons and promote the signal transmission between neurons. Its mechanism of action includes the regulation of neurotransmitter acetylcholine, thereby enhancing cognitive function.
intramuscular
oral
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06704334