RecruitingNot ApplicableNCT06706115

Effect of Intranasal Breast Milk Administration in Preterm Infants

: Effect of Intranasal Breast Milk Administration on Cerebral Oxygenation, Vital Signs and Transition Time to Full Oral Feeding in Preterm Babies: Randomized Controlled Study

Sponsor

Selcuk University

Enrollment

40 participants

Start Date

Jun 30, 2024

Study Type

INTERVENTIONAL

Conditions

Breast Feeding Nursing Caries Newborn; Vitality

Summary

The aim of the study was to investigate the effect of intranasal breast milk administration on cerebral oxygenation level, vital signs and time to full oral feeding in preterm infants.

Eligibility

Min Age: 28 WeeksMax Age: 37 Weeks

Inclusion Criteria6

Birth weight \>1000 gr,
APGAR score \>7 at 5 minutes after birth,
Availability of breast milk,
No medical diagnosis affecting cerebral oxygenation (intraventricular hemorrhage, cardiovascular and neurological disorders, anemia),
No congenital anomalies or chromosomal abnormalities,
No congenital anomaly (such as cleft palate) affecting nasal patency.

Exclusion Criteria7

Being able to feed orally in all feedings
Being fed entirely on formula milk,
Administration of medication via the nasal route,
Being intubated or receiving continuous positive air pressure (CPAP) support,
Maternal substance abuse, alcohol abuse, HIV infection, untreated active tuberculosis, chemotherapy or radiotherapy treatment,
The mother has mastitis, breast trauma, abscesses or is taking any medication that passes into the milk,
The mother does not want to express milk.

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Interventions

OTHERIntranasal human breast milk

The information in the "Physiologic Parameter Follow-up Form" will be recorded by the investigator just 5 minutes before the intervention. The researcher will drip 0.2 ml of breast milk at room temperature (approximately 22 °C) into the nose of the infant lying in the supine position, 0.1 ml in the right nose-0.1 ml in the left nose. 5 minutes after the intervention (T1), 15 minutes after the intervention (T2) and 30 minutes after the intervention (T3), the data in the "Physiologic Parameter Follow-up Form" will be recorded by the researcher. After intranasal breast milk administration, the baby will be fed by the neonatal nurse as in routine practice. The implementation of the intervention in the study will last for three days and this process will be repeated three times every day (09.00, 12.00 and 15.00).