Tumor Regression Grade As Predictor of Adjuvant Therapy

This study looks at whether measuring how much a tumor has shrunk after pre-surgery treatment (called tumor regression grade) can predict whether patients with esophageal cancer need additional therapy after surgery. **You may be eligible if...** - You had surgery to completely remove your esophageal cancer (R0 resection) with lymph node removal - You received pre-surgery treatment such as radiation, chemoradiation, or immunotherapy - You have squamous cell carcinoma of the esophagus **You may NOT be eligible if...** - Your medical records or follow-up information are incomplete - You have been diagnosed with more than one primary cancer Talk to your doctor to see if this trial is right for you.