Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

This feasibility study tests a new type of targeted radiation therapy called PULSAR — which delivers large, precisely focused radiation doses spread out over several weeks — for lung tumors located near the central airways or major structures in the chest. **You may be eligible if...** - You are 18 or older with a confirmed lung cancer diagnosis - Your tumor is between 1.5 and 5 cm in diameter and located near the central lung (within 2 cm of the mediastinum, esophagus, or main airways) - You are in good general health (ECOG 0–2) - You are able to have MRI scans - You are willing to use contraception during and after treatment if applicable **You may NOT be eligible if...** - Your tumor is outside the central zone or does not meet size criteria - You cannot tolerate MRI - You do not have a histologically confirmed cancer diagnosis Talk to your doctor to see if this trial is right for you.