Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults
Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults: a Randomized, Placebo-controlled, Double-blind Study
Chang Gung Memorial Hospital
52 participants
Dec 9, 2024
INTERVENTIONAL
Conditions
Summary
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults. Specifically, it will assess the immediate and long-term effects of this stimulation on brainwave activity and cognitive performance. The study will explore the potential of gamma light stimulation as a non-pharmacological intervention for cognitive decline in aging populations.
Eligibility
Inclusion Criteria6
- \. Age over 55 years old.
- \. The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education.
- \. Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function.
- \. Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.).
- \. Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels.
- \. Voluntary to sign the Informed Consent Form.
Exclusion Criteria3
- \. Participants enrolled in any cognitive enhancement study within the past two months.
- \. Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.).
- \. Pregnant, or planning to become pregnant.
Interventions
Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06715995