Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression

Exclusion Criteria9

• Secondary myopia, such as a history of retinopathy of prematurity or other neonatal diseases; syndromic myopia with a known genetic disorder or connective tissue disease, such as Stickler syndrome or Marfan syndrome
• Strabismus or other binocular vision abnormalities
• Cloudy refractive media: cloudy cornea, cataract or intraocular lens surgery
• Eye diseases that affect retinal function: macular degeneration, diabetic retinopathy, retinal detachment, glaucoma or ocular hypertension, endophthalmitis, uveitis, optic neuropathy, etc.
• History of refractive surgery, internal eye surgery, laser therapy, vitreous injection, etc.
• diabetes, hypertension and other systemic disorders
• History of use of retinal toxic drugs, such as hydroxychloroquine, etc.
• Use of orthokeratology, atropine, multifocal frame glasses and other myopia control methods; children who are currently receiving atropine, orthokeratology, multifocal frame glasses and other myopia control treatment, can be enrolled after 2 weeks of treatment.
• Other reasons considered unsuitable for inclusion by the study physician, including but not limited to other ocular and systemic disease abnormalities