RecruitingNot ApplicableNCT06717659

Probiotics in Pulmonaty Rehabilitation for COPD

Probiotics in the Management of Pulmonary Rehabilitation for COPD: A Randomized Controlled Trial


Sponsor

Fu Jen Catholic University

Enrollment

60 participants

Start Date

Dec 5, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate various aspects of patients with chronic respiratory diseases undergoing pulmonary rehabilitation supplemented with probiotics. The focus will be on clinical physiological responses, functional performance, respiratory status assessments, nutritional status evaluations, body composition analyses, and biochemical blood parameters, with a primary emphasis on the anti-inflammatory response.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Willing to sign a written informed consent form.
  • Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines.
  • Undergoing pulmonary rehabilitation therapy for more than three months.

Exclusion Criteria6

  • Under 18 years old.
  • Diagnosed with neuromuscular diseases.
  • Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months.
  • Unable to cooperate with cardiopulmonary exercise testing.
  • Has other diseases or behavioral restrictions preventing participation in exercise training for over one year.
  • Assessed by a physician to have severe malnutrition or a significantly low BMI.

Interventions

OTHERprobiotic supplementation intervention

probiotic supplementation will be administered, while participants continue undergoing routine pulmonary rehabilitation therapy

OTHERstandard pulmonnary rehabilitation

undergo routine pulmonary rehabilitation without probiotics intervention


Locations(1)

Fu Jen Catholic University Hospital, Fu Jen Catholic University

New Taipei City, Taiwan

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