RecruitingPhase 1Phase 2NCT06719596

Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD

Probiotics Combined with Enteral Nutrition on Infectious Complications After Pancreaticoduodenectomy:a Single-centre, Prospective Randomised, Open, Parallel-controlled, Superiority Study


Sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Enrollment

68 participants

Start Date

May 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Probiotics combined with enteral nutrition reduces postoperative infectious complications in PD


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients greater than 18 years of age;
  • Indication for elective pancreaticoduodenal surgery;
  • Patients who understand the nature of the trial and are willing and able to provide written consent

Exclusion Criteria5

  • Current or recent (within the previous 1 month) use of probiotic-based products or antibiotic therapy medications.
  • Inability to tolerate PD due to cardiopulmonary function and other parameters
  • Received radiotherapy before surgery
  • Emergency PD surgery
  • Pregnant and breastfeeding women

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Interventions

DRUGBifidobacterium Bifidum Oral Capsule

enteral nutrition+Pre-operative + one week post-operative Oral Bifidobacterium bifidum live triple capsule, 4 capsules Oral BID


Locations(1)

321 Zhongshan Road, Nanjing Gulou Hospital, Gulou District, Nanjing, Jiangsu Province, China

Nanjing, Jiangsu, China

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NCT06719596