RecruitingPhase 4NCT06723145

Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation


Sponsor

Kyoto University

Enrollment

1,200 participants

Start Date

Jan 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the impact of perioperative aspirin continuation on clinical outcomes in patients with a history of coronary stent implantation who are scheduled for abdominal surgery.


Eligibility

Min Age: 20 Years

Inclusion Criteria2

  • Patients with a history of coronary stenting and scheduled for abdominal surgery
  • Patients on a single antiplatelet agent

Exclusion Criteria7

  • Patients on dual antiplatelet therapy (DAPT)
  • Patients on anticoagulation therapy
  • Patients with a history of stent thrombosis
  • Patients with CHADS2 score >= 5
  • Patients at extremely high risk of bleeding and unable to continue preoperative aspirin
  • Patients incapable of consent, including those under 20 years of age
  • Other patients for whom either discontinuation or continuation of antiplatelet agents is deemed inappropriate by the attending physician

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Interventions

DRUGAspirin

perioperative aspirin continuation

DRUGAspirin interruption

Aspirin interruption 5-7 days before surgery


Locations(1)

Kyoto University Hospital

Kyoto, Japan

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NCT06723145


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