Pleural Irrigation With a Novel Devise.
A Pilot Assessment of the Safety and Efficacy of Pleural Irrigation for Retained Pleural Infection Using a Novel Irrigation Device
Beth Israel Deaconess Medical Center
10 participants
May 25, 2025
INTERVENTIONAL
Conditions
Summary
Single-arm pilot trial of the use of intrapleural saline irrigation to treat retained pleural infections for patients with contraindications to standard of care intrapleural enzymatic therapy.
Eligibility
Inclusion Criteria2
- Retained pleural effusion identified via bedside ultrasound within the first 24 hours after chest tube insertion
- Patient is contraindicated from receiving intrapleural enzymatic therapy within the first 24 hours after chest tube insertion
Exclusion Criteria2
- Non-infectious cause of pleural fluid analysis findings listed above identified (e.g. malignancy)
- Post-procedural empyema or complicated parapneumonic effusion
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Interventions
patients will have a CLRTM port and CLRTM irrigator (CLR Medical, Calverton, MD, USA) added to their chest tube and atrium circuit to facilitate pleural irrigation.
Locations(1)
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NCT06727578