RecruitingNCT06728878

Analysis of Lymph Node Metastasis and Tumor Deposit in the Short Gastric Mesentery Following Total Gastrectomy for Gastric Cancer

Lymph Node Metastasis and Tumor Deposit in the Short Gastric Mesentery Following Total Gastrectomy With D2 Lymphadenectomy Plus Complete Mesogastric Excision for Gastric Cancer: A Prospective Observational Study


Sponsor

Jichao Qin

Enrollment

150 participants

Start Date

May 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to explore lymph node metastasis in the short gastric mesentery following total gastrectomy with D2 lymphadenectomy plus complete mesogastric excision, providing evidence-based medicine for standardizing lymph node dissection in gastric cancer.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is analyzing tissue samples from people who have had total gastrectomy (full stomach removal) for gastric cancer to understand how cancer spreads to lymph nodes and surrounding tissues. This research could improve how surgeons stage and treat stomach cancer in the future. **You may be eligible if...** - You are 18 to 85 years old - You have confirmed stomach (gastric) adenocarcinoma from a pre-surgery biopsy - Your cancer was assessed as stage cT2-4a, without distant spread - You had a total gastrectomy with D2 lymph node dissection - You are in reasonably good pre-surgical health (ASA class I-III) **You may NOT be eligible if...** - Your pre-surgery biopsy was negative for cancer - Your cancer was too advanced at the time of diagnosis (cT4b or with distant spread) - Your BMI is above 30 - You previously received chemotherapy or radiation before surgery - You had prior upper abdominal surgery - You have another active cancer - You declined surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

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NCT06728878


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