RecruitingNCT06729112

Pan-immune-inflammation Value (PIN) in Behçet's Disease and Its Correlation With Disease Activity


Sponsor

Assiut University

Enrollment

80 participants

Start Date

Dec 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Behçet's disease (BD) is a systemic vasculitis affecting both small and large blood vessels in the venous and arterial systems. It is a multiorgan disease with various manifestations, including mucocutaneous, articular, ocular, gastrointestinal, vascular, and neurological involvements. The aim of present study is to assess pan immune inflammation value (PIN) value in BD in comparison to healthy control ,assess the PIN value in association with demographics and clinical characteristics of Behcet patients and to assess the PIN value in association with disease activity.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Adult BD patients who fulfilling the criteria for the diagnosis by International Team for the Revision of the International Criteria for Bechet's Disease .
  • Accept to participate in the current study.

Exclusion Criteria5

  • Individuals with other autoimmune diseases.
  • Patients unwilling to participate in the study.
  • Patients less than 18 years old.
  • Patients with malignancy or infections.
  • Pregnancy and lactation

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Interventions

DIAGNOSTIC_TESTpan immune inflammation value

Using the ratio of neutrophil, monocyte, and platelet counts to lymphocyte count, NLR, MLR, and PLR were calculated. The pan immune inflammation value (PIV) was calculated by multiplying the neutrophil count by the platelet count and the monocyte count, and then dividing the result by the lymphocyte count.


Locations(1)

Assiut University Hospitals

Asyut, Egypt

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NCT06729112


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