RecruitingNot ApplicableNCT06729710

Prism Adaptation in Symptomatic Esophoria - Effect of Shorter Time Intervals and Surgical Outcomes Based on Prism Adaptation


Sponsor

Rigshospitalet, Denmark

Enrollment

100 participants

Start Date

May 19, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a prospective randomized study aiming to investigate the effect of prism adaptation before surgery for symptomatic esophoria on the number of reoperations, the occurrence of over- and under-correction after the first surgery, and symptom resolution. Additionally, we aim to define the optimal duration of prism adaptation.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria5

  • Patients with symptomatic esophoria who meet one or more of the following criteria:
  • Double vision
  • Asthenopia (eye strain)
  • Headaches related to esophoria
  • Worsening of symptoms during fatigue, sleep deprivation, reading, illness, or alcohol consumption.

Exclusion Criteria12

  • Age between 18 and 65 years at date of inclusion.
  • Accommodative esotropia or esophoria
  • Myopia exceeding 10 diopters in the most myopic meridian
  • Treatment with botulinum toxin in an eye muscle within four months prior to inclusion
  • Inability to undergo reliable orthoptic measurements or prism adaptation
  • Previous strabismus surgery
  • Pregnancy or breastfeeding within 12 months prior to inclusion
  • Myogenic disorders (including Myasthenia Gravis)
  • Restrictive strabismus (including previous eye muscle trauma or Graves' orbitopathy)
  • Eye muscle paresis
  • Maximum prism-adapted deviation angle >40 prism diopters (PD) in any gaze direction for distance
  • Maximum prism-adapted deviation angle with ≥20 PD difference between near and distance measurements

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREPrism adaptation test

Prism Adapation test for 1 hour in one group, and 4 hours in second group

PROCEDUREother

Surgery based on prism adaptation test of 1 hour in one group and 4 hours in second group


Locations(1)

Rigshospitalet

Copenhagen, Denmark

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06729710