RecruitingNot ApplicableNCT06730243

Retzius-sparing Robot-assisted Radical Prostatectomy With "Sandwich" Technique of Total Urethral Reconstruction Versus Standard Robot-Assisted Radical Prostatectomy Versus Laparoscopic Radical Prostatectomy Surgery: A Comparative Prospective Study of 300 Patients

To Evaluate the Impact of Retzius-sparing Robot-assisted Radical Prostatectomy With "Sandwich" Technique of Total Urethral Reconstruction on Early Recovery of Urinary Continence (UC) Compared to the Conventional Approach (Anterior Approach) and Laparoscopic Radical Prostatectomy for the Treatment of Clinically Localized Prostate Cancer (PCa).


Sponsor

Ministry of Science and Technology of the People´s Republic of China

Enrollment

300 participants

Start Date

Jan 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the impact of Retzius-sparing robot-assisted radical prostatectomy with "Sandwich" Technique of Total Urethral Reconstruction on early recovery of urinary continence (UC) compared to the conventional approach (anterior approach) and Laparoscopic Radical Prostatectomy for the treatment of clinically localized prostate cancer (PCa).Purpose: The trial compares outcomes between three groups.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing three different surgical techniques for prostate cancer removal: a nerve-sparing robotic prostatectomy approach (Retzius-sparing with 'sandwich' urethral reconstruction), standard robotic prostatectomy, and traditional laparoscopic surgery. The goal is to determine which approach best preserves urinary continence and sexual function after surgery. **You may be eligible if...** - You have been newly diagnosed with prostate cancer confirmed by biopsy - Surgery is recommended as the primary treatment - You are 80 years old or younger - You agree to be randomly assigned to one of the three surgical techniques - You are able to fill out questionnaires on your own and provide written consent **You may NOT be eligible if...** - You do not have sufficient knowledge of German - You have significant cognitive impairment - Your BMI is above 35 (severe obesity) - You have serious conditions like liver cirrhosis, a second cancer, or cancer stage T4 - You had a previous cancer diagnosis within the last 3 years - You received hormone therapy within the last 3 months - You are immunocompromised or have a history of intermittent self-catheterization - You have chronic urinary infection or are on dialysis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERetzius-sparing robot-assisted radical prostatectomy and "Sandwich" Technique of Total Urethral Reconstruction

Retzius-sparing robot-assisted radical prostatectomy and "Sandwich" Technique of Total Urethral Reconstruction

PROCEDUREStandard Robot-Assisted Radical Prostatectomy

Standard Robot-Assisted Radical Prostatectomy

PROCEDURELaparoscopic Radical Prostatectomy

Laparoscopic Radical Prostatectomy


Locations(1)

National Cancer Center

Beijing, Beijing Municipality, China

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NCT06730243