Urinary Tubular Biomarkers for Chronic Kidney Disease
Erasmus Medical Center
556 participants
Jan 1, 2025
OBSERVATIONAL
Conditions
Summary
Currently used tests for chronic kidney injury only assess the function of one part of the kidney: the filter called the glomerulus. The other part, called the tubule, is disregarded. Based on many previous studies, the investigators have good reason to assume that a better prediction of the course of chronic kidney disease by testing tubular function will be possible. This is important, for example, when patients need to be treated with kidney-protecting drugs.
Eligibility
Inclusion Criteria1
- Chronic kidney disease stage 3 (eGFR 30-59ml/min)
Exclusion Criteria3
- Active glomerulonephritis treated with immunosuppression
- Kidney transplant recipient
- Current treatment with chemo- or immunotherapy for malignancy
Interventions
The urinary tubular test panel will be applied to urine samples that are collected as part of the routine outpatient follow-up. Its predictive power for CKD progression will be assessed. The results of the tubular test panel will not influence the treatment of the patients. They will remain under standard outpatient treatment throughout the study.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06732349