RecruitingPhase 2NCT06734975

Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery

Effect of Intraoperative Superior Laryngeal Nerve Blocks on Patient Outcomes in Microdirect Laryngoscopy for Benign Vocal Fold Lesions: A Randomized Trial


Sponsor

Rutgers, The State University of New Jersey

Enrollment

28 participants

Start Date

Jul 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery. Symptoms such as how much coughing or pain patients have after surgery, as well as whether patient's voice gets better will be interrogated.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Patient is aged 18 years or older at time of consent
  • Patient has suspected or confirmed benign vocal fold lesion
  • Patient is planning to undergo direct laryngoscopy with excision of the vocal fold lesion
  • Patient is English or Spanish speaking
  • Patient is not pregnant per self report
  • Patient is not incarcerated

Exclusion Criteria7

  • Patient is not 18 years of age or older at consent date
  • Patient does not speak English or Spanish
  • Patient is currently pregnant or plans to become pregnant prior to their study procedure
  • Patient has a laryngeal malignancy or found to find a laryngeal malignancy on final pathology
  • Patient will not be undergoing direct laryngoscopy with excision of lesion
  • Patient is unable to provide consent or complete study activities
  • Patient is incarcerated

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Interventions

DRUGSuperior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension)

Patients will receive a superior laryngeal nerve block consisting of 1 ml of 0.25% bupivacaine and 1mL of triamcinolone acetate 40 mg/ml to the neck on the side of the vocal cord lesion during their surgery.

DRUGSuperior laryngeal nerve block - Placebo (saline)

Patients will receive a saline placebo of 2mL saline to the neck on the side of the vocal cord lesion during their surgery.


Locations(1)

Rutgers New Jersey Medical School

Newark, New Jersey, United States

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NCT06734975