RecruitingNot ApplicableNCT06736106

Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?

ORTHOSPINE FITNESS: Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?


Sponsor

Istituto Ortopedico Rizzoli

Enrollment

200 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The present study is related to the project "ORTHOSPINE FITNESS: WHICH MARKERS OF MUSCULOSKELETAL HEALTH CAN EXPLAIN COMPLICATIONS IN SPINE SURGERY?", winner of the Ministry of Health Call, financed by the European Union, "M6/C2\_CALL 2023", Project Code " PNRR- MCNT2-2023-12378098", Call section "Non-chronic chronic diseases transmissible diseases (MCnT2) with a high impact on health systems". Complications of spinal surgery still represent a significant and unsolved problem. Their incidence is between 7 and 20%, with a high percentage of mechanical complications observed in patients operated on for degenerative pathologies. Readmissions, re-operations and subsequent rehabilitation treatments have a heavy impact on patients and the entire healthcare system.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age >= 18 years;
  • diagnosis of degenerative pathology of the spinal column of the thoraco-lumbo-sacral tract;
  • patients candidates for surgical treatment for the aforementioned pathology during the study period;
  • willingness to participate in the study and sign the specific informed consent

Exclusion Criteria3

  • presence of tumors or infections in the spinal column;
  • presence of degenerative pathology of the spine without surgical indication;
  • presence of degenerative pathology of the spinal column at the cervical level.

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Interventions

OTHERscreening

Comprehensive screening of bone metabolic status and bone fragility in the largest cohort to date of patients with degenerative spinal diseases


Locations(2)

Istituto Ortopedico Rizzoli

Bologna, Italy

Azienda ospedaliera universitaria Luigi Vanvitelli

Naples, Italy

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NCT06736106