RecruitingNot ApplicableNCT06736678

Oral Immunonutrition Therapy to Reduce Acute Toxicity After Neoadjuvant Chemoradiotherapy Pancreatic Cancer Patients

Efficacy of Oral Immunonutrition Therapy in Reducing Acute Toxicity After Neoadjuvant Chemoradiotherapy Among Pancreatic Cancer Patients: a Prospective, Single-arm Clinical Trial


Sponsor

Sun Yat-sen University

Enrollment

98 participants

Start Date

Aug 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

A prospective, single-arm clinical trial is conducted to investigate the role of oral immunonutrion in reducing acute toxicity after neoadjuvant chemoradiotherapy among pancreatic cancer patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether oral immunonutrition supplements — special nutritional formulas that support the immune system — can reduce the toxic side effects of chemoradiation therapy in patients with pancreatic cancer. **You may be eligible if...** - You have a confirmed diagnosis of pancreatic ductal cancer - You are receiving chemoradiation therapy — either before surgery (neoadjuvant) or as your main treatment if surgery is not possible - You have some signs of nutritional risk (NRS2002 score ≥3) - You are 18 years of age or older and in reasonably good health (ECOG 0–1) **You may NOT be eligible if...** - You are not receiving chemoradiation - Your nutritional status is adequate (low NRS2002 score) - You are in poor general health or have very short life expectancy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTOral Immunonutrition

Patients receive enteral immunonutrition, Oral Impact® Nestle for 6 weeks from one week before radiotherapy;


Locations(2)

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

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NCT06736678


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