RecruitingNot ApplicableNCT06742021

Application of DCE-MRI Based on 4D FreeBreathing in Predicting the Efficacy of Immune and Targeted Therapy in Lung Cancer


Sponsor

Yunnan Cancer Hospital

Enrollment

195 participants

Start Date

Nov 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to address the challenge of predicting the efficacy of targeted and immunotherapy in lung cancer patients. By utilizing two DCE-MRI images-one before treatment and one after one treatment cycle-along with the patients' clinical and pathological information, we aim to achieve accurate prediction of the therapeutic efficacy of targeted and immunotherapy in lung cancer patients.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria2

  • Tumor size greater than 2 cm
  • Age between 18 and 75 years

Exclusion Criteria3

  • Presence of MRI contraindications (e.g., metal implants, pacemaker implantation, etc.)
  • Allergy to gadolinium contrast agents
  • Lesions difficult to delineate on images due to conditions such as atelectasis or diffuse lesions

Interventions

DIAGNOSTIC_TESTApplication Value of MRI Imaging in Treatment Decision-Making for Lung Cancer

Chest MRI scans outside of the standard treatment protocol


Locations(1)

Yunnan Cancer Hospital

Kunming, Yunnan, China

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NCT06742021


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