RecruitingNCT06747000

Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders

Lipoprotein Functions in Healthy Individuals and Subjects With Lipid Disorders


Sponsor

The Miriam Hospital

Enrollment

80 participants

Start Date

Jul 18, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications. The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.


Eligibility

Min Age: 18 YearsMax Age: 69 Years

Inclusion Criteria4

  • Healthy volunteers
  • Abnormalities in lipid panels
  • Able to provide informed consent
  • Between the age of 18 and 69

Exclusion Criteria5

  • Drug or alcohol abuse within 6 months or significant mental/psychological impairment
  • Current smokers
  • Subjects with known bleeding disorders (for example, hemophilia)
  • Subjects requiring regular transfusions for any reason
  • No ethnic/racial groups will be excluded

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Locations(2)

Brown University Health Lipid Clinic

East Providence, Rhode Island, United States

Cardiovascular Research Center

Providence, Rhode Island, United States

View Full Details on ClinicalTrials.gov

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NCT06747000