RecruitingNot ApplicableNCT06748963

Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

Exercise Training Before (Fasted) Versus After (Fed) Breakfast in Type 1 Diabetes


Sponsor

University of Alberta

Enrollment

20 participants

Start Date

Jan 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how exercising in a fasted state (before eating) affects blood sugar levels in people with Type 1 diabetes who are on an insulin pump. Researchers want to understand whether this approach is safe and beneficial for blood sugar management. **You may be eligible if...** - You have had Type 1 diabetes for at least 5 years - You use an insulin pump and have been on the same method for at least 2 months - Your HbA1c (average blood sugar level over 3 months) is between 7.0% and 9.9% - You are overweight or have a larger waist measurement indicating central obesity - You use rapid- or ultra-rapid-acting insulin **You may NOT be eligible if...** - You have Type 2 diabetes or another form of diabetes - You have significant cardiovascular disease, kidney disease, or other major health complications - You are pregnant or planning to become pregnant - You are unable to share your continuous glucose monitor (CGM) data with the research team Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALFasted Exercise

Participants will complete three sessions of combined resistance-aerobic exercise per week. Sessions will always start with resistance training followed by aerobic training, and will increase in duration throughout the intervention period, so that by the final three weeks of the intervention, all participants accumulate 150 minutes per week of moderate intensity aerobic exercise and 75 minutes of resistance exercise per week. Participants will complete three distinct resistance exercise sessions per week, which will increase in load, but decrease in repetition range throughout the trial. The aerobic component of the exercise sessions will increase in duration from 35 to 50 minutes per session. Participants will walk on a treadmill at a speed and incline that corresponds to 70-80% of ventilatory threshold.

BEHAVIORALPostprandial Exercise

Participants will complete three sessions of combined resistance-aerobic exercise per week. Sessions will always start with resistance training followed by aerobic training, and will increase in duration throughout the intervention period, so that by the final three weeks of the intervention, all participants accumulate 150 minutes per week of moderate intensity aerobic exercise and 75 minutes of resistance exercise per week. Participants will complete three distinct resistance exercise sessions per week, which will increase in load, but decrease in repetition range throughout the trial. The aerobic component of the exercise sessions will increase in duration from 35 to 50 minutes per session. Participants will walk on a treadmill at a speed and incline that corresponds to 70-80% of ventilatory threshold.


Locations(1)

University of Alberta

Edmonton, Alberta, Canada

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NCT06748963


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