RecruitingNCT06751498

The Value of a Convolutional Neural Network-Based Renal Artery Perfusion Model in Predicting Renal Function After Partial Nephrectomy: A Prospective Study

The Value of a Renal Artery Perfusion Model Based on Convolutional Neural Network in Predicting Renal Function After Partial Nephrectomy: A Prospective, Single-Center Study


Sponsor

Shao Pengfei

Enrollment

300 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to develop a CNN-based machine module to predict postoperative fractional renal function in people who are proposed to undergo partial nephrectomy. The main question it aims to answer is: • Does this machine learning model accurately predict renal function after partial nephrectomy?


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an AI-based computer model — trained to analyze CT images of kidney blood vessel patterns — can predict how well the kidney will function after a partial nephrectomy (surgery to remove only the tumor while preserving the rest of the kidney). This could help surgeons plan better and counsel patients before surgery. **You may be eligible if...** - You have been diagnosed with a small kidney tumor (clinical stage T1, confirmed on CT or MRI) - You are scheduled to undergo partial nephrectomy (kidney-sparing surgery) - Your cancer has not spread to lymph nodes or other organs - You are in good health for surgery (ECOG 0–1) and have a life expectancy of more than 10 years - Your kidney function before surgery is normal (eGFR at or above 90 mL/min) **You may NOT be eligible if...** - Your tumor cannot be surgically removed - Your pre-surgery kidney function is below normal - You have received targeted therapy, immunotherapy, or chemotherapy before or after surgery - Your surgery is converted to full kidney removal during the procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)

Nanjing, Jiangsu, China

The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)

Nanjing, Jiangsu, China

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NCT06751498


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