Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy
Intraoperative Autonomic Blockade to Prevent Early Postoperative Pain After Laparoscopic Cholecystectomy: A Double-Blind, Randomized Controlled Trial
Universidad Simón Bolívar
60 participants
Jan 15, 2025
INTERVENTIONAL
Conditions
Summary
This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.
Eligibility
Inclusion Criteria1
- Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or without cholecystitis.
Exclusion Criteria4
- Associated biliary pathologies (e.g., biliary pancreatitis, cholangitis).
- Additional procedures, such as formal bile duct exploration. Conversion to an open approach
- Anesthesia or Surgical complications that require intensive care unit
- Allergies to local anesthetics
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Interventions
Autonomic nerve block performed with: * Bupivacaine: 20 mL of 0.5%. * Dexamethasone: 8 mg.
Locations(2)
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NCT06753500