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RecruitingNot ApplicableNCT06757218

Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).

Comparison of Autogenous Dentin Graft With Albumin Platelet Rich Fibrin Versus Autogenous Dentin Graft With Platelet Rich Fibrin in Alveolar Socket Preservation: A Randomized Controlled Clinical Trial.

Sponsor

Kafrelsheikh University

Enrollment

60 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Alveolar Socket Preservation

Summary

The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used. Autogenous dentin, taken from the patient, supports healing and bone regrowth. Platelet-rich fibrin (PRF), made from the patient's blood, enhances healing and bone density by releasing growth factors. A new technique combining L-PRF with albumin creates a stable healing membrane that provides a steady release of growth factors. Overall, these methods improve recovery after tooth extractions and prepare sites for future dental work.

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria6

  • Medically free patients.
  • Adult patients above 18 Years to 60 Years.
  • Non-restorable tooth indicated for extraction.
  • Posterior mandibular teeth.
  • Inactive infection related to the tooth.
  • Cooperative patients.

Exclusion Criteria4

  • Presence of any systemic disease that could influence the outcome of the therapy.
  • Presence of any risk factor (smoker, pregnant and lactating patients).
  • Patients with bone diseases.
  • Patients with poor oral hygiene.
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Interventions

OTHERempty socket

Patients will be left socket empty without any graft materials for spontaneous healing process after tooth extraction

PROCEDUREAutogenous Dentin Graft with Platelet Rich Fibrin

Patients will be inserting autogenous dentin graft and platelet rich fibrin in the socket after extraction.

PROCEDUREAutogenous Dentin Graft with Albumin Platelet Rich Fibrin

Patients will be inserting autogenous dentin graft and Albumin Platelet Rich Fibrin in the socket after extraction.

Locations(1)

Kaferelsheikh University

Kafr ash Shaykh, Kafrelsheikh, Egypt

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NCT06757218