RecruitingNot ApplicableNCT06761274

Study of Epigenetic and Inflammatory Markers of Accelerated Biological Ageing in the Follow up of Patients With Hodgkin's Lymphoma

Study of Epigenetic and Inflammatory Markers of Accelerated Biological Ageing in the Follow-up of Patients With Hodgkin's Lymphoma in Complete Remission for at Least 2 Years


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

200 participants

Start Date

Nov 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Study design: It is a monocentric and exploratory study, experimental on human tissues in vitro which involves the analysis of peripheral blood in patients with Hodgkin's lymphomas with the following characteristics: * in complete remission for at least two years after first-line therapy with stage IIb, III or IV at onset (Ann Arbor classification). * newly diagnosed (stage IIb, III or IV, Ann Arbor Classification).


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • hodgkin lymphoma stage II b, III or IV at onset in remission for at least two years after the first line of therapy for lymphoma
  • Newly diagnosed histologically confirmed stage II b, III or IV patients who require first-line therapy
  • Patients of both sexes aged ≥ 18 years at enrollment
  • Signature of informed consent

Exclusion Criteria1

  • Concomitant second neoplasm

Interventions

OTHERperipheral blood sampling

It is a monocentric and exploratory study, experimental on human tissues in vitro and similar projects do not exist in the literature. This study involves the analysis of peripheral blood in patients with hodgkin lymphoma with the following characteristics: * in complete remission for at least two years after first-line therapy with stage II b, III or IV at onset (Ann Arbor classification). * newly diagnosed (stage II b, III or IV, Ann Arbor Classification).


Locations(1)

IRCCS Azienda Ospedaliero - Universitaria di Bologna

Bologna, Italy

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NCT06761274


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