RecruitingNot ApplicableNCT06768749

The Impact of Melatonin Lotion on Sleep and Mental Health

The Impact of Melatonin Lotion on Actigraphy, Sleep Quality, Autonomic Nervous System Indicators, Mood, Anxiety Symptoms, and Side Effects


Sponsor

University of Redlands

Enrollment

60 participants

Start Date

Feb 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.


Eligibility

Min Age: 18 YearsMax Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a melatonin-containing lotion applied to the skin before bedtime can improve sleep quality and reduce anxiety and depression symptoms. Participants will apply the lotion nightly and track their sleep and mood over a set period. **You may be eligible if...** - You have measurable sleep problems (T-score of 48 or higher on a sleep disturbance scale) - You also have mild or greater anxiety or depression symptoms (T-score of 55 or higher) - You are not currently taking any medications for sleep, anxiety, or depression (including melatonin supplements) - You are not pregnant - You are willing to maintain a relatively consistent bedtime during the study **You may NOT be eligible if...** - You are already using antidepressants, anti-anxiety medications, or sleep aids - You are pregnant - You have allergies or sensitivities to scented lotion - You are unwilling or unable to commit to a regular sleep schedule during the study period Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMelatonin lotion

3 g lotion applied one hour before bedtime

OTHERPlacebo lotion

3 g of placebo lotion (scent-matched control) applied one hour before bedtime


Locations(1)

University of Redlands

Redlands, California, United States

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NCT06768749


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