RecruitingNCT06775808

Total Infectome Characterization of Eye Infections

Total Infectome Characterization of Eye Infections: a Metagenomic Sequencing Based Observational Study


Sponsor

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Enrollment

200 participants

Start Date

Dec 25, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Multiple pathogens can cause eye infection. In recent years, emerging and resurging viral infections represent an important public health problem. Many emerging viruses cause infectious diseases involving ophthalmic manifestations, including Mpox virus, Zika, Ebola, and SARS-CoV-2. Broad and unbiased pathogen surveillance is essential, so we design this unbiased metagenomic sequencing based study to investigate the total infectome of eye infections. The study is historical and prospective in design.


Eligibility

Inclusion Criteria2

  • Patients with a clinical diagnosis of one or more types of eye infections (including acute conjunctivitis, keratitis, uveitis, and endophthalmitis).
  • Biological samples has been collected for clinical microbiological examination, or consented to participate in this study.

Exclusion Criteria1

  • \. Patients who have no historically clinical surplus specimens.

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Locations(1)

Shanghai General Hospital

Shanghai, Shanghai Municipality, China

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NCT06775808


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