Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.
Impact of Ultra-processed Foods in a Population of Patients With Chronic Rheumatic Diseases (Rheumatoid Arthritis, Spondyloarthritis, Osteoarthritis).
Hospices Civils de Lyon
240 participants
Mar 31, 2025
OBSERVATIONAL
Conditions
Summary
Ultra-processed foods (UPF) represent one of the mainstays of today's diet. They are defined by the NOVA classification system. It was demonstrated that UPF consumption was associated with activity of inflammatory bowel diseases with underlying mechanisms not fully identified yet. It is suspected that UPF constituents could modify the gut microbiota, increase intestinal barrier permeability and directly engage immune surveillance systems, effects that could individually or synergistically increase the risk of immunomediated diseases. As some pathophysiological mechanisms are shared among IBD and rheumatic diseases, we have wondered if UPF consumption could be associated with increased risk of rheumatic disease and/or with their activity. Our primary aim will be to study the pattern of UPF consumption in patients with rheumatic diseases. Our secondary objectives will be to study the activity of diseases according to UPF consumption.
Eligibility
Inclusion Criteria3
- Age \> 18 years
- chronic rheumatic disease (Rheumatoid arthritis, spondyloarthritis, osteoarthritis)
- ability to perform questionnaires
Exclusion Criteria3
- Judicial protection measure
- Refusal to participate in the study
- Suffering from 2 rheumatic disease simultaneously
Interventions
Self administered dietary questionnaire at baseline, 6 and 12 months.
Self administered questionnaire of disease activity at baseline, 6 and 12 months.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06776965