RecruitingNCT06776965

Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.

Impact of Ultra-processed Foods in a Population of Patients With Chronic Rheumatic Diseases (Rheumatoid Arthritis, Spondyloarthritis, Osteoarthritis).


Sponsor

Hospices Civils de Lyon

Enrollment

240 participants

Start Date

Mar 31, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Ultra-processed foods (UPF) represent one of the mainstays of today's diet. They are defined by the NOVA classification system. It was demonstrated that UPF consumption was associated with activity of inflammatory bowel diseases with underlying mechanisms not fully identified yet. It is suspected that UPF constituents could modify the gut microbiota, increase intestinal barrier permeability and directly engage immune surveillance systems, effects that could individually or synergistically increase the risk of immunomediated diseases. As some pathophysiological mechanisms are shared among IBD and rheumatic diseases, we have wondered if UPF consumption could be associated with increased risk of rheumatic disease and/or with their activity. Our primary aim will be to study the pattern of UPF consumption in patients with rheumatic diseases. Our secondary objectives will be to study the activity of diseases according to UPF consumption.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether eating a diet high in ultra-processed foods (packaged snacks, fast food, sugary drinks, processed meats) affects the severity and outcomes of chronic rheumatic diseases such as rheumatoid arthritis, spondyloarthritis (spine inflammation), and osteoarthritis (joint wear-and-tear). **You may be eligible if...** - You are over 18 years old - You have a confirmed diagnosis of rheumatoid arthritis, spondyloarthritis, or osteoarthritis - You are able to complete questionnaires about your diet and health **You may NOT be eligible if...** - You are under a judicial protection order - You refuse to participate - You have two different rheumatic diseases at the same time Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERDietary Questionnaire

Self administered dietary questionnaire at baseline, 6 and 12 months.

OTHEREvaluation of disease activity (DAS-28, ASDAS, EVA, number of swollen joints, number of painful joint, nocturnal pain, morning stiffness)

Self administered questionnaire of disease activity at baseline, 6 and 12 months.


Locations(1)

Edouard Herriot Hospital

Lyon, France

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NCT06776965


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