Osteoarthritis Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about Osteoarthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting
Not Applicable

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Rheumatoid ArthritisOsteoarthritisTraumatic Arthritis+3 more
DePuy Orthopaedics118 enrolled5 locationsNCT06631638
Recruiting
Early Phase 1

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

DepressionKnee Osteoarthritis
University of California, Los Angeles30 enrolled1 locationNCT06906939
Recruiting

Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty

Osteoarthritis, KneePosttraumatic ArthropathyJoint Diseases+1 more
Aesculap AG140 enrolled1 locationNCT05980442
Recruiting

Evaluation of the PHENO4U Data Platform in Patients Undergoing Total Knee Arthroplasty

Rheumatoid ArthritisDegenerative OsteoarthritisPosttraumatic Arthropathy+3 more
Aesculap AG600 enrolled4 locationsNCT05302934
Recruiting

Anatomical Axis on X-Ray and Its Relationship With Pain and Kinesiophobia in Knee Osteoarthritis

PainKnee OsteoarthritisKinesiophobia
Selim Sezikli100 enrolled1 locationNCT07168590
Recruiting
Not Applicable

Geniculate Artery Embolization for Osteoarthritis

ArthritisOsteo Arthritis KneeOsteoarthritis+1 more
University of Minnesota20 enrolled1 locationNCT04456569
Recruiting

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

Rheumatoid ArthritisOsteoarthritis, KneePolyarthritis+6 more
Zimmer Biomet760 enrolled16 locationsNCT05787821
Recruiting

Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis

Cardiovascular DiseasesOsteoporosisThrombosis+12 more
Guang'anmen Hospital of China Academy of Chinese Medical Sciences100 enrolled1 locationNCT07301892
Recruiting

Prepare II - Predictive Model Training and External Validation

HIP AND KNEE OSTEOARTHRITIS
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio400 enrolled1 locationNCT07304323
Recruiting

Exactech Shoulder Post Market Clinical Follow-up Study

Rheumatoid ArthritisInfectionsAnkylosing Spondylitis+6 more
Exactech20,000 enrolled38 locationsNCT05603728
Recruiting

Study to Evaluate the Performance of Navigated TKA With OrthoPilot® pheno4u TKA Level 1

Osteoarthritis, KneePosttraumatic ArthropathyJoint Diseases+1 more
Aesculap AG120 enrolled4 locationsNCT06955481
Recruiting
Phase 3

ZILRETTA in Subjects With Shoulder Osteoarthritis

Glenohumeral Osteoarthritis
Pacira Pharmaceuticals, Inc150 enrolled32 locationsNCT06269705
Recruiting

Clinical and Radiological Outcomes of Medacta Shoulder System FR

FractureRheumatoid Arthritis ShoulderPrimary Osteoarthritis+4 more
Medacta International SA200 enrolled1 locationNCT05926622
Recruiting

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

Rheumatoid ArthritisOsteoarthritis, Hip
University of Turku110 enrolled4 locationsNCT05278520
Recruiting

Clinical Orthopaedic Data Bank (Acute and Chronic)

OsteosarcomaCerebral PalsyOsteoarthritis+1 more
University of Florida10,000 enrolled1 locationNCT00411060
Recruiting
Not Applicable

Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

Osteoarthritis ShoulderAvascular Necrosis of the Head of HumerusRheumatoid Arthritis Shoulder
Catalyst OrthoScience90 enrolled3 locationsNCT04968405
Recruiting
Phase 4

Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes

Diabetes Mellitus, Type 2Osteoarthritis, Knee
University of Kansas Medical Center120 enrolled1 locationNCT06478186
Recruiting
Not Applicable

G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study

Osteoarthritis, HipTotal Hip ArthroplastyDegenerative Joint Disease of Hip+5 more
Zimmer Biomet300 enrolled11 locationsNCT04754087
Recruiting
Not Applicable

Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort

Parkinson DiseaseJoint OsteoarthritisAtherosclerosis of the Distal Arteries, Without Gangrene+2 more
University Hospital, Clermont-Ferrand5,000 enrolled1 locationNCT04375280
Recruiting
Not Applicable

Positive Minds Strong Joints for Knee Osteoarthritis

Osteoarthritis, Knee
Boston University Charles River Campus40 enrolled1 locationNCT06493903