RecruitingNCT06780046

Study That Will Evaluate the Brazilian Population With COPD.

Prospective Multicentric Cohort Study of Severe and Very Severe COPD Patients in Brazil.


Sponsor

AstraZeneca

Enrollment

693 participants

Start Date

Jan 31, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Observational, prospective, multicenter cohort study with consecutive inclusion of COPD patients. Eligible patients will be those with severe and very severe COPD according to the GOLD 2024 (Global Initiative for Chronic Obstructive Lung Disease) guidelines being followed at participating hospitals. The severity of COPD is related to the exacerbation rate, which in turn is related to the progression of the disease and the occurrence of complications and death. There is no national data on this subgroup.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a database of patients with COPD (chronic obstructive pulmonary disease) in Brazil to better understand how the disease presents, progresses, and is managed in the Brazilian population. The information collected may help doctors develop better, locally tailored treatment guidelines. **You may be eligible if...** - You are 18 years of age or older, male or female - You have been diagnosed with COPD based on breathing tests (spirometry) showing airflow obstruction - You have significant symptoms (CAT score of 10 or higher) or significant airflow limitation (FEV1 below 50%) - You have had at least one severe flare-up (requiring hospitalization) or at least two moderate flare-ups per year **You may NOT be eligible if...** - You have severe scarring of the lungs (advanced fibrosing interstitial lung disease) - You have high-risk pulmonary hypertension requiring triple therapy - You are currently receiving active treatment for cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(10)

Research Site

Aparecida de Goiânia, Brazil

Research Site

Bahia, Brazil

Research Site

Belém, Brazil

Research Site

Brasília, Brazil

Research Site

Campo Grande, Brazil

Research Site

Florianópolis, Brazil

Research Site

Goiânia, Brazil

Research Site

Santo André, Brazil

Research Site

São Paulo, Brazil

Research Site

Uberlândia, Brazil

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NCT06780046


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