RecruitingNot ApplicableNCT06781892

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial


Sponsor

Lars Wiuff Andersen

Enrollment

909 participants

Start Date

Mar 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Out-of-hospital cardiac arrest
  • Age ≥ 18 years
  • ≥ 1 manual defibrillation attempt by emergency medical services
  • Shockable rhythm as the last known rhythm
  • Two manual defibrillators present on-site

Exclusion Criteria3

  • Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of the cardiac arrest
  • Prior enrollment in the trial
  • Posterior pad placement not deemed possible by on-site clinician

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Interventions

OTHERAnterior-lateral pad positioning

Defibrillation pads positioned anterior-lateral

OTHERAnterior-posterior pad positioning

Defibrillation pads positioned anterior-posterior

OTHERDouble-sequential defibrillation

Combination of anterior-lateral and anterior-posterior pad positioning for a total of 4 pads and 2 shocks.


Locations(6)

Emergency Medical Services, the North Denmark Region

Aalborg, Denmark

Danish Air Ambulance, Danish Regions

Aarhus N, Denmark

Prehospital Emergency Medical Services, Central Denmark Region

Aarhus N, Denmark

Copenhagen Emergency Medical Services, the Capital Region of Denmark

Ballerup Municipality, Denmark

The Prehospital Center, Region Zealand

Næstved, Denmark

Emergency Medical Services, the Region of Southern Denmark

Vejle, Denmark

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NCT06781892


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