RecruitingNCT06783127

Clinical Outcomes of Use of Olaparib in Castration Resistant Prostate Cancer

Clinical Outcomes of Use of Olaparib in Castration Resistant Prostate Cancer: An Observational Study


Sponsor

Santa Chiara Hospital

Enrollment

3,000 participants

Start Date

Jan 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is an observational, retrospective/prospective, multicenter study designed to define, overall survival, clinical outcomes and predictive/prognostic factors of a consecutive population of mCRPC patients treated with olaparib in clinical practice.


Eligibility

Sex: MALE

Plain Language Summary

Simplified for easier understanding

This observational study is reviewing real-world clinical outcomes of men with BRCA-mutated metastatic castration-resistant prostate cancer (mCRPC) who were treated with olaparib — a targeted PARP inhibitor drug — in routine clinical practice rather than in a trial setting. **You may be eligible if...** - You are a male patient with metastatic castration-resistant prostate cancer - You have a BRCA gene mutation (hereditary or tumor-based) - You received olaparib as part of routine clinical care (not a clinical trial) **You may NOT be eligible if...** - You received olaparib within the context of a clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOlaparib

Olaparib given according the clinical practice to BRCA positive mCRPC patients


Locations(2)

Sabrina Rossetti

Naples, Italy

Orazio Caffo

Trento, Italy

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NCT06783127


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