RecruitingPhase 2NCT06784336

Phase II Study of Resistant Potato Starch Plus Deferasirox to Improve Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation

Phase II Multi-center Study of Resistant Potato Starch Plus Deferasirox to Improve Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation


Sponsor

University of Michigan Rogel Cancer Center

Enrollment

50 participants

Start Date

Oct 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The study will evaluate the safety and early efficacy of administering the combination of a commercially available potato-based resistant starch along with iron chelation therapy to subjects undergoing alloHCT.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Iron chelation and a drug called Potato Resistant Starch for people with allogeneic stem cell transplant. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIron chelation

Patients will receive Iron chelation with deferasirox (Jadenu 7 mg/kg/day preferred versus Exjade 10 mg/kg/day) beginning on day -14 and continuing through day +100

DRUGPotato Resistant Starch

Patients will receive PRS beginning on day -6 and continuing through day +100. Patients will take 20g packet twice daily


Locations(1)

University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, United States

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NCT06784336


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