The Effect of Resistance Training on Sarcopenia in Older Heart Failure Patients
The Effects of Machined Based Resistance Training in Older Patients With Chronic Heart Failure With Sarcopenia
Kieu Nguyen Dang Phuong
146 participants
Dec 24, 2024
INTERVENTIONAL
Conditions
Summary
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
Eligibility
Inclusion Criteria4
- Aged ≥ 60 years old
- Meet the diagnostic criteria of 2019 AWGS2 sarcopenia, can be diagnosed once meeting (1) + (2) or (1) + (3) or (1) + (2) + (3): (1) Appendicular skeletal muscle mass (ASM): dual-energy X-ray absorptiometry (DXA) (male \<7.0 kg/m², female \<5.7 kg/m²). (2) Muscle strength: handgrip strength (male \<28.0 kg, female \<18.0 kg). (3) Physical performance: 6-meter walking speed \<1.0 m/s.
- Meet the diagnostic criteria of heart failure following ESC 2021.
- Clearly understand the content and purpose of the study and sign the informed consent form.
Exclusion Criteria26
- Early stage after acute coronary syndrome (within the first 2 days)
- Unstable coronary artery disease
- Decompensated heart failure
- Acute venous thrombosis or recent arterial embolism (pulmonary or systemic)
- Acute myocarditis, pericarditis, endocarditis
- Aortic dissection of the valve
- Severe symptomatic aortic stenosis
- Acute systemic disease or fever
- Uncontrolled or life-threatening atrial or ventricular arrhythmias (including new-onset atrial fibrillation or flutter)
- Uncontrolled tachycardia (resting heart rate \> 120 beats per minute)
- Third-degree AV block
- Uncontrolled diabetes
- Symptomatic orthostatic hypotension (\> 20 mmHg)
- Gradually increasing fatigue during exercise or dyspnea at rest or with exertion within the past 3-5 days
- Significant myocardial ischemia at low workloads \< 2 METs or 50W
- Relative contraindications according to ACSM 2022:
- Weight gain ≥ 1.8 kg in the past 1-3 days
- Simultaneous use of continuous or intermittent Dobutamine
- Decrease in blood pressure with exercise
- NYHA IV heart failure
- Complex ventricular arrhythmias at rest or with exertion
- Resting heart rate ≥ 100 bpm when lying down
- Comorbidities that limit exercise
- Severe obstructive hypertrophic cardiomyopathy
- Have participated in a cardiovascular rehabilitation program within the last 6 months
- Do not agree to participate in the study
Interventions
The participants will receive HF treatment as prescribed by cardiologists. If participants have any additional medical conditions, their existing medications or treatments should continue. They are also asked to maintain their usual physical activity, exercise routines, and dietary habits, without making changes outside of the study intervention. At the beginning, patients participating in resistance training should complete a pretest of one-repetition maximum (1-RM) to assess muscle strength, which will be used by a professional physical therapist to develop an individualized prescription. The specific movements are as follows: (1) leg press and (2) calf raise by Proxomed Compass 540 (Germany); (3) leg curl, (4) chest press, (5) push up, (6) seated row by HUR machine (US). During the 8 weeks, subjects will train 3 non-consecutive days/week with intensity 30%1-RM to 60% 1-RM, 3 sets/one excercise with 8-12 repetitions.
Locations(2)
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NCT06785168