Chronic Heart Failure Clinical Trials

46 recruiting

Chronic Heart Failure Trials at a Glance

44 actively recruiting trials for chronic heart failure are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Moscow, Vandœuvre-lès-Nancy, and Multiple Locations. Lead sponsors running chronic heart failure studies include Bayer, Montreal Heart Institute, and National Medical Research Center for Cardiology, Ministry of Health of Russian Federation.

Browse chronic heart failure trials by phase

Treatments under study

About Chronic Heart Failure Clinical Trials

Looking for clinical trials for Chronic Heart Failure? There are currently 46 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic Heart Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic Heart Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting
Not Applicable

Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure

Chronic Heart FailureSarcopenia in Elderly
Kieu Nguyen Dang Phuong146 enrolled2 locationsNCT06785168
Recruiting

A Study to Learn More About the Safety of the Drug Vericiguat in Japanese People With Chronic Heart Failure Who Will be Receiving Vericiguat Under Real-world Conditions

Chronic Heart Failure
Bayer1,400 enrolled1 locationNCT05666518
Recruiting

An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting

Chronic Heart Failure With Reduced Ejection Fraction
Bayer1,350 enrolled1 locationNCT06148935
Recruiting

National Heart Failure Registry

Chronic Heart Failure
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation20,000 enrolled1 locationNCT06683001
Recruiting

Entresto Tablets and Granules for Pediatric Specified Drug-use Survey (Pediatric Chronic Heart Failure)

Pediatric Chronic Heart Failure
Novartis Pharmaceuticals30 enrolled28 locationsNCT06659393
Recruiting
Phase 1

Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

Chronic Heart Failure
Melana Yuzefpolskaya, MD40 enrolled1 locationNCT07490054
Recruiting
Not Applicable

Non-invasive Ventilation and High-speed Oxygen Therapy Effects on Heart Function - HiFlow-Heart Study

Chronic Heart Failure
University Hospital, Rouen30 enrolled1 locationNCT04471129
Recruiting

AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices

Cardiovascular DiseasesHeart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University of Salerno205 enrolled1 locationNCT06909682
Recruiting

Observational Study Designed to Detect Decompensation of Congestive Heart Failure (dCHF) Using a Non-Invasive Wearable Device

Decompensated Chronic Heart Failure
CHFDX,Inc.60 enrolled2 locationsNCT07350759
Recruiting

Biomarkers as Predictors of Chronic Heart Failure in Patients With Type 2 Diabetes

Type 2 DiabetesChronic Heart Failure
Regionshospital Nordjylland500 enrolled1 locationNCT04941794
Recruiting
Not Applicable

Biventricular or Left Bundle Branch Pacing to Assess the Effect of Cardiac Resynchronization Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation

Chronic Heart Failure
Semmelweis University Heart and Vascular Center360 enrolled1 locationNCT07434193
Recruiting
Phase 4

Vericiguat and Reverse Remodeling Indices in Heart Failure

Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana60 enrolled1 locationNCT07405944
Recruiting

A Study to Learn More About How Safe Finerenone is and How Well it Works in Adults With Chronic Heart Failure in South Korea

Chronic Heart Failure
Bayer300 enrolled1 locationNCT07379840
Recruiting
Not Applicable

Impact of YOGA on the Quality of Life and Well-being of Heart Failure Patients

Chronic Heart Failure
Assistance Publique - Hôpitaux de Paris66 enrolled1 locationNCT06019169
Recruiting
Phase 1Phase 2

A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure

Chronic Heart FailureCoronary Artery Bypass Grafting (CABG)Chronic Ischemic Cardiomyopathy
Tasly Pharmaceutical Group Co., Ltd51 enrolled4 locationsNCT07265349
Recruiting
Not Applicable

Effectiveness of Low -Versus High -Volume High -Intensity Interval Training in Patients With Chronic Heart Failure

Chronic Heart Failure
Cairo University45 enrolled1 locationNCT07325942
Recruiting
Phase 4

The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)

Chronic Heart FailureIron Deficiency, Latent
Tomsk National Research Medical Center of the Russian Academy of Sciences100 enrolled1 locationNCT05793996
Recruiting
Not Applicable

Comparing the Effects of Combining Cognitive and Physical Exercise Training on Cognition, and Cerebral Blood Flow Regulation in Men and Women With Chronic Heart Failure

AgingChronic Heart Failure
Montreal Heart Institute216 enrolled1 locationNCT04970888
Recruiting
Not Applicable

The HEARTFELT Study

Heart FailureChronic Heart Failure
Heartfelt Technologies1,500 enrolled3 locationsNCT06222099
Recruiting
Phase 4

Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure

Iron-deficiencyChronic Heart FailureLeft Ventricular Systolic Dysfunction
Raffaele De Caterina60 enrolled1 locationNCT06270498