RecruitingPhase 2Phase 3NCT06785298

Fexofenadine as Adjuvant Therapy in Parkinson Disease

Clinical Study to Evaluate the Possible Efficacy and Safety of Fexofenadine in Patients With Parkinson's Disease Treated With Conventional Treatment


Sponsor

Tanta University

Enrollment

46 participants

Start Date

Dec 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Parkinson's disease (PD) is a chronic, progressive neurological disorder characterized by both motor and non-motor symptoms. PD is the second most common neurodegenerative disorder after Alzheimer's disease and the most common movement disorder. PD has age-related pathology; it is present in 1-2% of the population over 60 years of age. The disease is characterized by a triad of disordered voluntary motor activity in the form of bradykinesia (slowness of movement) or even akinesia (absence of movement),rigidity and postural instability, and a resting tremor of the hands and less commonly the feet.


Eligibility

Min Age: 50 YearsMax Age: 70 Years

Interventions

DRUGLevodopa/carbidopa

A dopamine precursor, was first developed for the treatment of PD in the 1960s and continues to be the most-effective therapeutic agent for PD

DRUGFexofenadine

Fexofenadine is a second-generation antihistamine that does not penetrate the CNS and has the least CNS side effects among the second-generation antihistamines


Locations(1)

Tanta University

Tanta, Egypt

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NCT06785298


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