RecruitingNCT06786039

Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants

Sponsor

Korea University Anam Hospital

Enrollment

80 participants

Start Date

Jan 20, 2025

Study Type

OBSERVATIONAL

Conditions

Preterm infant

Summary

This is a prospective observational study investigating the impact of NIV-NAVA on short-term clinical outcomes and long-term neurodevelopment in very preterm infants.

Eligibility

Min Age: 1 HourMax Age: 48 Hours

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Non-invasive NAVA for people with preterm infant. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 1 Hour to 48 Hours.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURENon-invasive NAVA

Initiate respiratory assist with NIV-NAVA within 48 hours. The setting of respiratory support will be adjusted based on clinical conditions of each subject. NIV-NAVA could be switched to nasal continuous airway pressure or high flow nasal cannula, and it also could be stopped after initial stabilization. In cases of respiratory distress syndrome, lung surfactant will be administered via the less invasive surfactant administration (LISA) method and avoid endotracheal intubation whenever possible. For who intubated in the delivery room, extubation with NIV-NAVA should be considered as soon as possible. Endotracheal intubation with invasive ventilation could be applied when clinical deteriorations happens.