RecruitingNCT06787456

"Xijiang Project" Screening Cohort for NPC

Establishment of "Xijiang Project" Million-Person Screening Cohort for Nasopharyngeal Carcinoma

Sponsor

Ming-Yuan Chen

Enrollment

1,000,000 participants

Start Date

Nov 14, 2024

Study Type

OBSERVATIONAL

Conditions

Screening Nasopharyngeal Carcinoma (NPC)

Summary

The purpose of this study is to establish a comprehensive and integrated nasopharyngeal carcinoma screening cohort, which includes an epidemiological information database containing basic information, gender, age, ethnic and family history, dietary and lifestyle habits, and geographical environmental factors; a biobank of blood, tissue fluid, swabs, etc., for Epstein-Barr virus, tumors, and genetics; a clinical examination database including nasopharyngoscopy, imaging, pathology, and other examinations; and databases of Epstein-Barr virus and human genetic sequencing, etc.

Eligibility

Min Age: 30 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Clinical examinations for high-risk participants, EBV DNA test, and others for people with nasopharyngeal carcinoma (npc) and screening. The study is currently recruiting participants at 1 location. People eligible for this study include aged 30 Years to 69 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTEBV antibodies test

Test for VCA-IgA, EBNA1-IgA, EA-IgA, Zta-IgA, Rta-IgG and P85-Ab in nasopharyngeal brushing and plasma in plasma, saliva and nasopharyngeal brushing.

DIAGNOSTIC_TESTEBV DNA test

quantitative polymerase chain reaction, methylation sequencing and target sequencing of EBV DNA in nasopharyngeal brushing, saliva and plasma.

OTHERepidemiological information survey

epidemiological information survey including basic conditions, dietary and lifestyle habits, social, geographical, environmental, and other information.

OTHERClinical examinations for high-risk participants

nasopharyngoscopy, head and neck MRI.

OTHEREBV and human genetic sequencing

EB virus and human genetic sequencing for plasma, etc.