RecruitingNCT06788652

A Study of Patients With Relapsed/Refractory Mantle Cell Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting

Non-interventional Cohort Study of Patients Treated With Lisocabtagene Maraleucel (Liso-cel) for Relapsed/Refractory Mantle Cell Lymphoma in the Post-Marketing Setting


Sponsor

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Enrollment

300 participants

Start Date

Feb 4, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to understand the long-term safety and effectiveness of lisocabtagene maraleucel (liso-cel) for the treatment of Mantle Cell Lymphoma (MCL).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting real-world information on patients with a blood cancer called mantle cell lymphoma (MCL) who received a CAR-T cell therapy called lisocabtagene maraleucel (liso-cel) in a commercial (non-trial) setting. CAR-T therapy reprograms the patient's own immune cells to hunt down cancer. The study documents how well this treatment works in everyday clinical practice. **You may be eligible if...** - You have relapsed or refractory mantle cell lymphoma (cancer that came back or did not respond to prior treatment) - You received at least one infusion of liso-cel as a commercially approved treatment in the United States - Your treatment followed the FDA-approved dose and guidelines **You may NOT be eligible if...** - You were participating in another investigational study at the time you received liso-cel - The CAR-T cell product you received did not meet commercial quality specifications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALLisocabtagene maraleucel

According to US Prescribing Information


Locations(1)

Center for International Blood and Marrow Transplant Research (CIBMTR)

Milwaukee, Wisconsin, United States

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NCT06788652


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