RecruitingNCT06788821

Prenatal Ultrasonographic Assessment of Fetal Thyroid in Patients With Thyroid Pathology


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

440 participants

Start Date

Jun 12, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to evaluate the possibility to use prenatal ultrasonography for diagnosis and prognostic guidance in cases of suspected fetal thyroid changes in fetuses belonging to women with thyroid disease and women with low obstetric risk (i.e., pregnancy not complicated by maternal and/or fetal pathology) between 14 and 37 gestational weeks. The main question it aims to answer is: Is it possible to diagnose thyroid disease in fetuses early using measurable parameters of the fetal thyroid through ultrasonography?


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Inclusion Criteria4

  • Participants between 14 and 37 gestational weeks, who will be followed for the entire period of pregnancy, up to delivery, at the same enrolling center
  • Obtaining informed consent for participation in the study
  • Maternal age between 18 and 45 years (extremes included)
  • Participants with good understanding of the Italian language

Exclusion Criteria6

  • Smoking participants
  • Patients with BMI\>30
  • Absence of correct dating of pregnancy within the first trimester
  • Pathological conditions (e.g., malabsorptive or socioeconomic conditions that may interfere with fetal growth)
  • Twin pregnancy
  • Only for the low obstetric risk group of patients: Fetus with malformative pathology

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Interventions

DIAGNOSTIC_TESTDescription of the trend of major thyroid ultrasound biometric parameters

Use of prenatal ultrasonography for diagnosis and prognostic guidance in suspected fetal thyroid changes.


Locations(2)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, Italy

Ospedale Santa Chiara - Trento

Trento, Italy, Italy

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NCT06788821


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