Exploring the Tumor Micro-Environment with 68Ga-FAPi-46 PET/CT in Breast Cancer

This study is testing a new type of PET scan called 68Ga-FAPi-46 PET/CT — which highlights the tissue surrounding tumors rather than the cancer cells themselves — to see how well it maps the environment around breast cancer tumors. This could help doctors better understand how each tumor behaves and plan more targeted treatments. **You may be eligible if...** - You are a woman aged 18 or older - You have newly diagnosed, biopsy-proven invasive breast cancer - Your tumor is larger than 2 centimeters - Your cancer involves the lymph nodes under your arm - You have already had or are scheduled to have a standard FDG PET/CT scan - You are a candidate for surgery or pre-surgery chemotherapy **You may NOT be eligible if...** - You are pregnant or breastfeeding - You cannot lie flat for the duration of a PET scan - Your biopsy tissue is unavailable for analysis - You have certain conditions that prevent participation Talk to your doctor to see if this trial is right for you.