Effects of Ventilator Hyperinflation Versus Vibrocompression in Mechanically Ventilated Patients
Effects of Ventilator Hyperinflation Versus Vibrocompression on Lung Compliance in Mechanically Ventilated Patients
Cairo University
81 participants
Feb 1, 2025
INTERVENTIONAL
Conditions
Summary
The aim of the current study is to compare the effects of ventilator hyperinflation and vibrocompression on lung compliance in mechanically ventilated patients.
Eligibility
Inclusion Criteria3
- Eighty-one mechanically ventilated patients more than 48 hours up to 7 days
- Their ages range from 35 to 55 years old.
- Medical stability (mean arterial pressure > 60 < 110, systolic blood pressure > 80, diastolic blood pressure > 60, fraction of inspired oxygen < 60, positive end expiratory pressure (PEEP) <10)
Exclusion Criteria10
- Patients will be excluded if they have the following conditions or diseases:
- Unstable hemodynamics
- Fraction of inspired oxygen (FiO2) ≥ 0.6
- PEEP ≥ 10 cmH2O
- undrained pneumothorax and hemothorax or subcutaneous emphysema
- Pulmonary pathology (e.g., acute respiratory distress syndrome, exacerbation of chronic obstructive pulmonary disease, and acute pulmonary edema)
- Unstable neurological problems (raised intracranial pressure).
- Lung Cancer
- Recent/unhealed rib fracture
- Any disease obstructs our study.
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Interventions
In ventilator hyperinflation volume control mode, the ventilator will be set to eight breaths per minute, and the tidal volume will be increased to deliver hyperinflation breaths that are 15 ml/kg, as will be calculated using the predicted body weight. Tidal volume will be increased in 150-ml increments until a peak airway pressure of 40 cmH2O is achieved. Once this pressure is reached, eight mechanical breaths will be delivered to the patient. After this, the ventilator will be reset to pretreatment variables, and the patient will be rested for 30 s. The sequence will be repeated. The treatment will consist of five sets of eight ventilator hyperinflation breaths.
Vibrocompression will be performed by the physical therapist to produce vibration and will be combined with compression of the patient's chest in the expiratory phase. Every vibrocompression will be interrupted at the end of each expiratory phase to allow free inspiration.
Percussion, Postural Drainage, and Suction
Locations(1)
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NCT06791798