RecruitingNCT06794970

Tissue Study on the Chronic Active Humoral Rejection (cAMR) Population of Kidney Transplantation


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

50 participants

Start Date

May 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The study is tissue-based, retrospective and prospective, single-centre, non-sponsored. Primary objective: To examine patient and organ survival and eGFR variation in kidney transplant patients diagnosed histologically with cAMR.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age ≥18 years
  • Kidney transplant recipients
  • eGFR>15 ml/min/1.73 sq m at the time of diagnosis of cAMR
  • cAMR diagnosis defined on the basis of the 2018 Banff Classification (17), made after 1/1/2018.
  • Obtaining Informed Consent to Participation.

Exclusion Criteria2

  • Combined transplant patients (heart-kidney, liver-kidney or kidney-pancreas)
  • Histological evidence of concomitant disease (e.g. recurrence of original nephropathy or diagnosis of 'de novo' nephropathy, acute cellular rejection, polyomavirus BK nephropathy, other)

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Locations(1)

IRCCS Sant'Orsola University Hospital - Nephrology, Dialysis and Transplant Unit

Bologna, BO, Italy

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NCT06794970


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