RecruitingNot ApplicableNCT06796270

Hypofractionated Radiotherapy for Nasopharyngeal Carcinoma

Efficacy and Safety of Hypofractionated Radiotherapy for Nasopharyngeal Carcinoma


Sponsor

The Second Affiliated Hospital of Hainan Medical University

Enrollment

24 participants

Start Date

Feb 20, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study was to evaluate the efficacy and safety of large fractionation radiotherapy in nasopharyngeal carcinoma patients, and to analyze whether Hypofractionated radiotherapy is not inferior to conventional radiotherapy.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study tests a "hypofractionated" radiation therapy approach — delivering higher doses per session over fewer visits — for people with nasopharyngeal carcinoma (cancer at the back of the nasal cavity, behind the nose). The goal is to see if this schedule is as effective as traditional longer courses with fewer side effects. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with nasopharyngeal carcinoma confirmed by biopsy - You have at least one measurable tumor on imaging - You are in reasonably good health (performance status 0-2) - Your blood counts and organ function (liver, kidneys) are within acceptable levels - Your expected survival is 6 months or more **You may NOT be eligible if...** - Your blood counts or organ function do not meet required thresholds - You have another serious or unrelated medical condition - You are not healthy enough to tolerate radiation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONHypofractionated radiotherapy

The patients with nasopharyngeal carcinoma were given the dose of large segmentation radiotherapy, 2.64Gy/ time, 5 times/week, a total of 25 times, a total of 66Gy/5 weeks.


Locations(1)

The Second Affiliated Hospital of Hainan Medical University

Haikou, Hainan, China

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NCT06796270


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