COMBO Endoscopy Oropharyngeal Airway Reduces Hypoxia During Sedated Gastrointestinal Endoscopy in Obese Patients: A Multicenter, Randomized, Controlled Clinical Trial

This study tests a special mouthpiece (oropharyngeal airway device) inserted during sedated endoscopy (camera examination of the stomach and colon) in overweight patients to see if it reduces episodes of low oxygen levels. Obese patients are at higher risk for breathing problems during sedation, and this device aims to keep the airway open. **You may be eligible if...** - You are between 18 and 70 years old - Your BMI is 28 or higher (overweight to obese range) - You are scheduled to have both a gastroscopy (stomach camera) and colonoscopy under sedation - You are in generally good health (ASA classification I or II) - The procedure is expected to take 45 minutes or less **You may NOT be eligible if...** - You have a bleeding disorder or are prone to mouth/nose bleeding - You have severe heart, kidney, or liver problems - You have chronic obstructive pulmonary disease (COPD) or other significant respiratory conditions - You have anatomical features in your mouth or throat that prevent device placement Talk to your doctor to see if this trial is right for you.